ESR1 Rabbit Polyclonal Antibody(0803-1)
货号:0803-1 ,雌激素受体 α (ERα),也称为 NR3A1,是两种主要雌激素受体之一,是一种由雌激素激活的核受体。它对性发育和生殖功能至关重要,并参与乳腺癌、子宫内膜癌和骨质疏松等病理过程。
货号:0803-1 ,雌激素受体 α (ERα),也称为 NR3A1,是两种主要雌激素受体之一,是一种由雌激素激活的核受体。它对性发育和生殖功能至关重要,并参与乳腺癌、子宫内膜癌和骨质疏松等病理过程。
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产品名称 | ESR1 Rabbit Polyclonal Antibody |
ESR1 兔多克隆抗体 | |
抗体类型 | Rabbit Polyclonal Antibody |
兔多克隆抗体 | |
免疫原 | Recombinant protein within C terminal human estrogen receptor |
人雌激素受体 C 端重组蛋白 | |
种属反应性 | Human |
人类 | |
验证应用 | WB, IF-Cell, IHC-P |
蛋白质印迹 (WB)、细胞免疫荧光 (IF-Cell)、免疫组化 (IHC-P) | |
分子量 | Predicted band size: 66 kDa |
预测条带大小:66 kDa | |
阳性对照 | MCF-7, human breast tissue, SK-Br-3 |
MCF-7、人乳腺组织、SK-Br-3 | |
偶联 | Unconjugated |
非偶联 | |
RRID | AB_3068649 |
AB_3068649 | |
- 形态 | Liquid |
液体 | |
- 浓度 | 1ug/ul |
1ug/ul | |
- 存放说明 | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
解冻后储存于 +4℃。分装后储存于 -20℃ 或 -80℃。避免反复冻融。 | |
- 存储缓冲液 | 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
1*PBS (pH7.4), 0.2% BSA, 40% 甘油。防腐剂:0.05% 叠氮化钠。 | |
- 亚型 | IgG |
IgG | |
- 纯化方式 | Immunogen affinity purified |
免疫原亲和纯化 | |
- WB | 1:2,000 |
1:2,000 | |
- IHC-P | 1:100 |
1:100 | |
- IF-Cell | 1:50 |
1:50 | |
靶点 | |
- 功能 | Estrogen receptor alpha (ERα), also known as NR3A1, is one of two main types of estrogen receptor, a nuclear receptor activated by estrogen. It is essential for sexual development and reproductive function, and is involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. |
雌激素受体 α (ERα),也称为 NR3A1,是两种主要雌激素受体之一,是一种由雌激素激活的核受体。它对性发育和生殖功能至关重要,并参与乳腺癌、子宫内膜癌和骨质疏松等病理过程。 | |
背景文献 | 1. Karas RH, et al. Circulation, 1994 2. Grohe C, et al. Br J Pharmacol, 1997 |
1. Karas RH, 等. Circulation, 1994 2. Grohe C, 等. Br J Pharmacol, 1997 | |
序列相似性 | Belongs to the nuclear hormone receptor family. NR3 subfamily. |
属于核激素受体家族,NR3 亚家族。 | |
组织特异性 | Widely expressed. Isoform 3 is not expressed in the pituitary gland. |
广泛表达。亚型 3 在垂体中不表达。 | |
翻译后修饰 | Phosphorylation, glycosylation, ubiquitination, methylation, palmitoylation, etc. |
磷酸化、糖基化、泛素化、甲基化、棕榈酰化等。 | |
亚细胞定位 | Nucleus, Cytoplasm, Cell membrane |
细胞核、细胞质、细胞膜 | |
UNIPROT # | SwissProt: P03372 Human |
SwissProt: P03372 人类 | |
别名 | DKFZp686N23123 antibody, ER alpha antibody, ER antibody, ER-alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESR1_HUMAN antibody, ESRA antibody, Estradiol receptor antibody |
DKFZp686N23123 抗体, ER alpha 抗体, ER 抗体, ER-alpha 抗体, Era 抗体, ESR 抗体, ESR1 抗体, ESR1_HUMAN 抗体, ESRA 抗体, 雌二醇受体抗体 |
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