ESR1 Rabbit Polyclonal Antibody(0803-1)

货号:0803-1 ,雌激素受体 α (ERα),也称为 NR3A1,是两种主要雌激素受体之一,是一种由雌激素激活的核受体。它对性发育和生殖功能至关重要,并参与乳腺癌、子宫内膜癌和骨质疏松等病理过程。

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产品名称ESR1 Rabbit Polyclonal Antibody

ESR1 兔多克隆抗体
抗体类型Rabbit Polyclonal Antibody

兔多克隆抗体
免疫原Recombinant protein within C terminal human estrogen receptor

人雌激素受体 C 端重组蛋白
种属反应性Human

人类
验证应用WB, IF-Cell, IHC-P

蛋白质印迹 (WB)、细胞免疫荧光 (IF-Cell)、免疫组化 (IHC-P)
分子量Predicted band size: 66 kDa

预测条带大小:66 kDa
阳性对照MCF-7, human breast tissue, SK-Br-3

MCF-7、人乳腺组织、SK-Br-3
偶联Unconjugated

非偶联
RRIDAB_3068649

AB_3068649
- 形态Liquid

液体
- 浓度1ug/ul

1ug/ul
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

解冻后储存于 +4℃。分装后储存于 -20℃ 或 -80℃。避免反复冻融。
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

1*PBS (pH7.4), 0.2% BSA, 40% 甘油。防腐剂:0.05% 叠氮化钠。
- 亚型IgG

IgG
- 纯化方式Immunogen affinity purified

免疫原亲和纯化
- WB1:2,000

1:2,000
- IHC-P1:100

1:100
- IF-Cell1:50

1:50
靶点
- 功能Estrogen receptor alpha (ERα), also known as NR3A1, is one of two main types of estrogen receptor, a nuclear receptor activated by estrogen. It is essential for sexual development and reproductive function, and is involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

雌激素受体 α (ERα),也称为 NR3A1,是两种主要雌激素受体之一,是一种由雌激素激活的核受体。它对性发育和生殖功能至关重要,并参与乳腺癌、子宫内膜癌和骨质疏松等病理过程。
背景文献1. Karas RH, et al. Circulation, 1994
2. Grohe C, et al. Br J Pharmacol, 1997

1. Karas RH, 等. Circulation, 1994
2. Grohe C, 等. Br J Pharmacol, 1997
序列相似性Belongs to the nuclear hormone receptor family. NR3 subfamily.

属于核激素受体家族,NR3 亚家族。
组织特异性Widely expressed. Isoform 3 is not expressed in the pituitary gland.

广泛表达。亚型 3 在垂体中不表达。
翻译后修饰Phosphorylation, glycosylation, ubiquitination, methylation, palmitoylation, etc.

磷酸化、糖基化、泛素化、甲基化、棕榈酰化等。
亚细胞定位Nucleus, Cytoplasm, Cell membrane

细胞核、细胞质、细胞膜
UNIPROT #SwissProt: P03372 Human

SwissProt: P03372 人类
别名DKFZp686N23123 antibody, ER alpha antibody, ER antibody, ER-alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESR1_HUMAN antibody, ESRA antibody, Estradiol receptor antibody

DKFZp686N23123 抗体, ER alpha 抗体, ER 抗体, ER-alpha 抗体, Era 抗体, ESR 抗体, ESR1 抗体, ESR1_HUMAN 抗体, ESRA 抗体, 雌二醇受体抗体


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